kiwipeel
kiwipeel
> Hi @kiwipeel , > > You can perform differential expression analysis at the pseudobulk levels between conditions and then use the obtained contrast level gene statistics as input for...
> Hi @kiwipeel , > > You could also do that, but if the objective is to compare conditions I would recommend to go the pseudobulk route since with it...
> Hi @kiwipeel , > > Indeed! We keep all of them since p-value thresholding is completely arbitrary, depending on the application you might want to use a more strict...
> It really depends on the downstream task you want to use them for, in your case since you are interested in contrasting conditions I would again recommend to do...
@plger For instance, gm42418 is an lncRNA gene associated with rRNA contamination. When I looked at the UMAP plot, I noticed that some cell clusters express this gene highly. In...
> Hi all, > > So I wanted to run cellchat per biological replicate. Mainly, it's because I am concerned that for some population, it can be defined as interacting...