Meijiao Wang

Hi all, Because the Jaccard similarity method is highly sensitive to sequencing depth of cells, so it is a must to normalize window-cell matrix to sequence depth of each cell....

How to improving similarity between snRNA-seq and snATAC-seq nuclei, by tuning parameters like 'k', 'lambda'?

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Hi, I found it is easily to integrate snRNA and snATAC nuclei with satisfactory consistency between data modalities (which is what we expected), if less then 10000 nuclei were fed....

Hi, I found it is easily to integrate snRNA and snATAC nuclei with satisfactory consistency between data modalities (which is what we expected), if less then 10000 nuclei were fed....

nn_index in scRNA-Projection-UMAP.zip is empty or not compatible with uwot 0.1.8 and RcppAnnoy 0.0.16

1

Dear Granja It is quite a smart idea to apply the 'uwot_transform' to _in situ_ projection of new data (disease sample of both single cell or bulk datasets) to a...

Hi, I understand that in the script scATAC_04_Compute_Gene_Scores.R, gene activity scores are calculated by the custom_cicero_cds function in a more efficient way and at the same time cell grouping information...

How did you compose those pretty scentific figures ?

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Hi, How did you compose those pretty scentific figures? like the panels f and g in your example figure, which show density tracks of scADT-seq and scRNA-seq. Did you plot...