kw10
kw10
Hi Marcos, I've tested my data with v1.1.10 and the plots are still empty. However, when running with test data from the Quick Start Example [here](https://osf.io/t6j7u/wiki/2.%20Quick%20Start%20Example/), the plots were fine....
Thank you, Marcos. I will email you some example data and I'll give SigProfilerAssignment a try.
Just a quick follow-up question regarding the custom database. In order to re-normalize the human WSG signatures to dog, would I do: for each 96 trinucleotides, count the number seen...
Thanks!
Hello, I am getting the same warning messages as #1 above. Has anyone come up with an explanation for this warning? Thanks!
There are 41 samples total and one gene is mutated in 22/41 (53.7%) and the other gene is mutated in 4/41 (9.1%).
Yes, all other genes have lower frequencies. Thanks for the explanation!
Hi Sander, Thanks for your reply and suggestions! I've now tried using DHB and BD (with the pairwise.discover.test) TP53 and RB1 did not come up significant. I then tried limiting...
Thank you, Sander, that is very helpful. In our case the malignant cohort has 23 samples and TP53 is mutated in 16; RB is mutated in 13 (all are co-mutated...