bzhousd

ColabFold MSA server error in AlphaFold2.ipynb

1

## Expected Behavior ColabFold MSA server returns results ## Current Behavior raise Exception(f'MMseqs2 API is giving errors. Please confirm your input is a valid protein sequence. If error persists, please...

chain break doesn't work as expected

13

I thought that if I add /0 in contig, that segment will become a separated chain in the result protein. for example , 'contigmap.contigs=[A229-445/0 B230-444/0 20-20/C70-328/50-50]' , RFDiffusion will generate...

How to emphasize on the structure?

1

Thank you for this great work. I learned a lot of insights of alphafold from openfold paper. I am predicting antibody-antigen complex. In my case, I already know the structure...

How to generate compact binders?

1

Thank you for your great work. I have been using rfdiffusion to design protein binders in my project, but I am having difficulty generating compact binders. I took an example...