LeilyR

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could you please provide the command line you have used

The reason is that you most likely have a very low amount of contacts between chromosomes on your matrix, so the obs/exp function underlying the --transform obs/exp returns all zero....

I am not sure if this about our tool or the latest comment on this issue. If you are talking about how we handle hicPCA after hicAdjustmatrix , this is...

Thanks for reporting it. I will have a look at it asap.

I believe that comes from some rounding in the last bin. I do not get how had issue downstream though. Can you elaborate a bit on that?

I labeled it, so we will have a deeper look at it.

For now you could give those numebrs all to `yMax`. It is possible to provide `yMin` and `yMax` with mutliple values

I wonder if using `--centerReads` along with `--Offset` and `--minFragmentLength/--maxFragmentLength` would already give you your desired output.

If I am not wrong its default behaviour is to merge bins of no coverage that is why you got bins of different length. To skip the those regions you...