AyushSaxena

Linclust fails to cluster sequences with a single mismatch

8

I'm currently testing linclust using the easy-linclust workflow with very small datasets (100 / 1000 sequences). Each sequence is a nucleotide sequence, on average, 3000 basepairs long. So using 20...

We have observed in our data (generated through multiple different Illumina machines and library prep methods), that local coverage density varies across the genome, predictably so, across all genotypes. When...

Overlapping deletions of the same size wrongly clustered

2

We have two overlapping deletions of size 22bp that we can identify with clear breakpoints on IGV. One is ~50% of the population, and the other is ~10%. However sniffles2...