Valeriu Ohan

The current default mpielup maximum depth is [8000](https://github.com/samtools/htslib/blob/c3ba3026d6cebc30bb6c50e6171473db3cd8d445/sam.c#L4720), which could be increased.

Add method sam_open_write

6

1. The new method `sam_open_write` can open a `htsFile` file in writing mode only, attach a header struct (`sam_hdr_t`) to it and write the header data to the disk, before...

Adds a new option to `samtools split` command, which allows the user to split reads into distinct files by a custom read tag (with a string type value). E.g. `samtools...

On Linux, uses the value of **TMPDIR** environment variable, when looking for the temporary folder. If not found or too long, falls back to `/tmp`. Fixes #1172

We had a [request](https://github.com/samtools/bcftools/issues/1452) from a BCFtools user to assist in splitting the chromosomes from a VCF file into smaller scaffolds, which can then be indexed in **TBI** format. The...

BC tags with "none" value

3

Hi! We found a BAM file, produced by Isaac 03.16.02.19, that contains BC tags with "none" value, which is invalid according to the [standard](https://github.com/samtools/hts-specs/blob/master/SAMtags.pdf), section 1.3. The barcodes appear to...