Leander

when i run `.plot_vs_ttest()` on my diffxpy object which I got from a wald test, I see the following error. I looked into this a bit and the culprit seems...

I have just tried running a wald test with a directly provided patsy design matrix. When I specified the size_factors argument, I got the following error (because sample_information is no...

int32 columns in obs break writing of adata to disk

1

if I convert a singlecellexperiment object with anndata2ri, obs columns which should be int32 have a weird dtype in pandas. this breaks writing the adata to disk with the fillowing...

localconverter error

2

Hi Phil! I just tried to convert my jupyter anndata2ri usage to a normal python script (i.e. using localconverter rather than ipython cell magics). I am, however, hitting an unexpected...

Error when batch_size[1] <= number of genes

2

when I run batchglm through diffxpy (diffxpy.test.wald()) and my dataset has less or equal the number of features as I have set as the second dimension of the batch size,...

Stop using multiprocessing for fitting dispersion models earlier

1

From experience, I can say that the multiprocessing overhead when fitting dispersion models seems to be a lot larger than the code is currently written for. ie. fitting the last...

Support chunked upload

1

Thanks so much for this amazing tool. As I'm using a commercially hosted nextcloud instance which means, I cannot upload files bigger than 10GB. I was wondering if you would...

DE section issues

1

I'm just looking at the DE section of the best practice book and noticed two potential issues with the aggregate_and_filter() function: The text says "For each patient we create 1...

Add scran nomalisation into scanpy

2

### What kind of feature would you like to request? New analysis tool: A simple analysis tool you have been using and are missing in `sc.tools`? ### Please describe your...

IO support for pandas datetime format

1

### Please make sure these conditions are met - [x] I have checked that this issue has not already been reported. - [x] I have confirmed this bug exists on...