José Marcos Moreno-Cabrera

Fails to map many variants when using VCF option

2

Hi, Congrats for the tool. I have observed a wrong behaviour when mapping a VCF from GRCH37 to GRCH38: 59 out of 249 variants failed to map: `Fail(REF==ALT)`. For example,...

Training a new model on panel data beyond Sig3

1

Hi! We are interested in training a new model for a different gene panel; the [guide](https://github.com/parklab/SigMA/wiki/Optimize) helped a lot. We want to detect other signatures beyond Sig3. I have read...

Hi! I am following the [tune example](https://github.com/parklab/SigMA/blob/master/examples/test_tune_example.R). We first provide our dataset to run SigMA and tune it based on our data. How big should our dataset be? The tcga_mc3_brca.maf...

Hi, Imagine this example in Django ORM: `myStudent.delete() ` If the delete action violated a foreign key constraint, Django will generate an exception (which is correct) but **SwampDragon will estimate...