INSA PathoGenomics

v6.2.0 not reporting "missing positions report"

2

Hello, Tb-profiler version v6.2.0 is not reporting "missing positions report" data in the .txt output (default settings). The data is generated in the .json file but in the .txt is...

Unreported deletion in pncA gene

1

Hello, I have a MTB strain with a large deletion in pncA gene, that should leed to LoF. In a previous version of tb-profiler this deletion reported resistance to Pyrazinamide...

Variant reported at wrong frequency

3

Hello, Tb-profiler v6.2.0 calls a variant in fbiC at 100% frequency, with associated resistance to Delamanid and Pretonamid, that only exists in 2 or 3 reads. 1305494 Rv1173 fbiC frameshift_variant&stop_lost&splice_region_variant...