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                                            Matthew Durrant

Clustering billions of sequences gets stuck on kmermatcher

Any thoughts on how would you combine clusters across batches?

createdb max number of sequences

Following up on this, running into the same issue. Any plans to increase the limit?

Inconsistent number of matching hashes

Oh I see, you calculate the jaccard similarity using a merge-sort approach. Couldn't you also just take the jaccard similarity of the two hash sets?

Phenotypes influencing each other

Or say hypothetically that 75% of the time, when an individual receives diagnosis A, then they'll also be diagnosed with B. Doesnt't having both A and B in the phenotype...

---Fatal error--- Mega::GetProfileByLabel(Cluster19) Segmentation fault (core dumped)

Can't share the structures unfortunately. But I decided to use the `-align` mode instead of `-super` and it didn't encounter the same error.