AndrewLawrence

Good spot! For programming use, the colon operator `1:x` is a bit unsafe as if `x` ever holds the value zero you would iterate through 1, 0 without (always) throwing...

> I am looking into it Amazing, thanks! > there would need to be a fixed (non-alpha) background color onto which all layers must be merged, resulting in a final...

Thanks, this is very helpful! I am approaching this from a regularisation perspective (to add confidence intervals to [Chen et al](https://www.biorxiv.org/content/10.1101/164327v2.full)'s "RME" method).