treangenlab
Some questions
Hello,
Thank you for making this program.
I would like to ask whether methphaser can only be used in phasing or can it be used directly in assembly? Because I found that in the meth_phaser_post_processing file, you defined a ‘chroms’, which seems to be only applicable to chr1-chr22. If the number of chromosomes exceeds 22 and there are thousands of chromosomes, can methphaser run normally?
Sorry the short answer is no. However, I think it is possible to pipe newly phased reads into assemblers.
Cheers,
Yilei Fu
Postdoctoral Associate Baylor College of Medicine Human Genome Sequencing Center
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On Jun 26, 2025, at 7:16 PM, Humonex @.***> wrote:
[https://avatars.githubusercontent.com/u/94833927?s=20&v=4]Humonex created an issue (treangenlab/methphaser#32)https://github.com/treangenlab/methphaser/issues/32
Hello,
Thank you for making this program.
I would like to ask whether methphaser can only be used in phasing or can it be used directly in assembly? Because I found that in the meth_phaser_post_processing file, you defined a ‘chroms’, which seems to be only applicable to chr1-chr22. If the number of chromosomes exceeds 22 and there are thousands of chromosomes, can methphaser run normally?
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Thank you. I have another question. I noticed that methphaser can run perfectly on human chromosomes. Can it run on other species with more than 22 chromosomes?