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feature request: only search within a list of potential peptides

Open avilella opened this issue 3 years ago • 2 comments

Hi,

Would it be possible for AfDesign to design peptides that bind a certain structure/domain but to do so for a given length and within a list (fasta file) of potential peptides?

AfDesign would not attempt a peptide that is not in the list, instead giving the best peptide within the list.

Thanks

avilella avatar Jun 28 '22 14:06 avilella

Not sure I completely follow... Are you looking to rank a list of peptide candidates (not redesign them?)

sokrypton avatar Jun 28 '22 16:06 sokrypton

Yes, one would explore the landscape of best peptide binders within a list (may be a very long list) of possible peptides of a given length.

On Tue, Jun 28, 2022 at 5:15 PM Sergey O @.***> wrote:

Not sure I completely follow... Are you looking to rank a list of peptide candidates (not redesign them?)

— Reply to this email directly, view it on GitHub https://github.com/sokrypton/ColabDesign/issues/40#issuecomment-1168927036, or unsubscribe https://github.com/notifications/unsubscribe-auth/AABGSN26XVAZJZBWYZHKCYDVRMQKJANCNFSM52COQDQQ . You are receiving this because you authored the thread.Message ID: @.***>

avilella avatar Oct 11 '22 08:10 avilella