Automargins cause imshow figure to jump around and change pixel size and labels spacing
I wasn't sure if this was a bug initially so I provided a reproducible example and closer description in the forum.
Briefly, with automargin=False, heatmaps of different figure sizes have the same pixel size:

Setting automargin=True creates figures with widely different pixel sizes and shifts where the figure appear and its whitespace (with more than just the label length):

The jumping around behavior and inconsistent pixel sizes both seem to come from a bug in how the automargins are calculated or applied. A workaround is to set automargin=False and then manually specifying how much space is needed for the labels in the margin dictionary, e.g. margin=dict(t=100, b=0, l=80, r=0) and pad the overall figure size with these numbers, e.g. height = 100 + cut * 30.
It seems like the automargins are not correctly adding their label padding to the overall figure size, so that would be my suggestion for what could be a possible solution here.
Example code:
import plotly.express as px
import numpy as np
import pandas as pd
np.random.seed(20934)
img = np.random.rand(200, 200)
for cut in [10, 50]:
fig = px.imshow(
img[:cut, :cut],
height=cut * 30,
width=cut * 30,
x = [''.join(np.random.choice(list('qwertyuioplkjhgfdsazxcvbnm,.;[098765432'), np.random.choice(40))) for x in range(cut)],
y = [''.join(np.random.choice(list('qwertyuioplkjhgfdsazxcvbnm,.;[098765432'), np.random.choice(40))) for x in range(cut)],
)
fig.update_layout(
coloraxis_showscale=False,
margin=dict(t=0, b=0, l=0, r=0),
xaxis_nticks=cut + 1,
yaxis_nticks=cut + 1,
).update_xaxes(
automargin=False,
).update_yaxes(
automargin=False,
)
fig.show()