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Nanopore Kmer Model and Consensus Sequence Generation with openDBA

Open N-damo opened this issue 1 year ago • 1 comments

Dear developers: openDBA has many applications, which are very interesting. Nanopore provides a kmer model for generating standard nanopore signals. By providing a sequence based on this kmer model, the corresponding standard nanopore signals can be generated. Traditional kmer models require sequencing a standard sequence, known as de Bruijn sequence, which includes all possible kmers. Initially, the current values of kmers are manually annotated and then iteratively corrected. Whether openDBA can generate a consensus sequence to obtain this kmer model without manual annotation? best regards Li'anLin

N-damo avatar May 20 '24 04:05 N-damo