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Multiple testing correction: modkit dmr

Open ericmsmall opened this issue 1 year ago • 2 comments

I want to clarify whether modkit DMR is applying any type of multiple testing correction following calculation of MAP-based p-values on at a per base resolution (ie., modkit dmr pair --ref --base A)?

ericmsmall avatar Mar 14 '24 22:03 ericmsmall

@ericmsmall There is no correction applied, the MAP-based p-values are all calculated independently and in isolation.

ArtRand avatar Mar 14 '24 23:03 ArtRand

Bumping, this could be more clearly mentioned in the docs. It could cause issues for those who don't bother to check and start publishing results without controlling for multiple testing. Thanks!

pre-mRNA avatar Dec 29 '24 03:12 pre-mRNA