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Ploidy and purity estimates
Following the example usage in the vignette, I retrieve the purity and ploidy estimates:
fit = emcncf(oo)
fit$purity
fit$ploidy
For some samples I get "75%" preceding the value. For example:
fit$purity
75%
0.3225428
fit$ploidy
75%
2.553525
For most samples, I only get the value. Can you tell me what the "75%" means?
Thanks
Can you tell me what the "75%" means?
It has nothing to do with tumor purity or ploidy. Instead, it stems from the fact that these parameters are estimated using the 75% quantile of some data, e.g.
> quantile(1:10, probs = 0.75)
75%
7.75
You can safely ignore the "75%" names attribute by, for instance, doing:
fit$purity <- unname(fit$purity)
fit$ploidy <- unname(fit$ploidy)
This is ideally something emcncf() should do internally to avoid this confusion.