ECNet
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An evolutionary context-integrated deep learning framework for protein engineering
hello! i follow you steps traind the model in the ./output/RRM/model_1 i want to know where can i find test result such like spearmans corr? If you have answered my...
Hello, I have a question to ask you, when I used **ccmpred example.psc example.mat -b example.braw -d 0** command to generate braw file, there was an error. Error: **unknown option...
When I was running code ,it encountered this problem.How can I solve it? 
Hello, In the ECNet paper, you built an unsupervised ECNet model that does not require DMS data for training. It uses the predicted probability of an amino acid at a...
Recently, I read this paper introducing the ECNet, and I think it has huge potetial for enzyme engineering. But, I have a question on the software. If I only have...
Hello, Thank you very much for sharing ECNet with the scientific community. Could you please provide more information about the 'Fitness Score' which is required in the **Fitness TSV file**...
Hello, In the ECNet paper, the possibility to generate higher-order mutant from training on low-order varaints data is demonstrated. However, the `MTH3_HAEAESTABILIZED_Tawfik2015` example provided only predicts single point mutations. Could...
Hello, what's the best way to generate predictions on new mutations? I have a data frame of double mutations to test but was not sure about the best way to...
In the Example 2 section of the README, based on the code you provided, my understanding is that this code can predict the corresponding score for the combinatorial mutants (multi-point...