Locally install and run AlphaFold
Hi, It is possible to install and run Alpha Fold on my local computer (not on VM or cloud) with the given specification: I9-12900 CPU 128gb ddr4-3200 Asus Prime Z690P 2tb NVME + 8TB HDD
Regards, Gal.
Based on those specs, you can probably run AlphaFold with reduced databases on your local computer, though if you do not have a dedicated graphics card it will probably be very slow.
Assuming you have a dedicated graphics card and do not need high speed results, you could also run with full databases on the HDD
I agree with @tcoates5: It should be possible to run AlphaFold on your machine, but without an (NVIDIA) GPU it will run the model inference and relaxation parts rather slowly. I recommend getting a GPU, ideally with a lot of GPU RAM.