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scaled or arcsinh-transformed expression for annotation?

Open hlmeng opened this issue 4 months ago • 0 comments

Thank you for developing this excellent tool.

In the manuscript, it suggested to use the heatmap from Figure 6 to annotate clusters, but we have a question regarding the use of scaled expression values (0-1). Since this scaling can artificially inflate low-expression markers, would using arcsinh-transformed values be a more appropriate method for cluster annotation?

hlmeng avatar Aug 25 '25 14:08 hlmeng