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Variaous length of inverse folding sequences

Open what-is-what opened this issue 1 year ago • 1 comments

We are currently using inverse folding in ESM3. When we increase the temperature from moderate 0.5 to 2 or 3, we see a wide range of sequence variation, which is very attractive. However, if the sequence length variation occurs in the process, the number mismatch with the atom coordinate leads to an error. We want to generate different sequence patterns regardless of the number of atom coordinates. Is this possible?

what-is-what avatar Nov 21 '24 02:11 what-is-what

ESM3 only operates on fixed length prompts.

ebetica avatar Dec 04 '24 22:12 ebetica