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feature request: ignore duplicate-marked reads

Open anoronh4 opened this issue 5 years ago • 1 comments

this issue is to request ignoring dup reads as an option. gatk best practice is to keep all duplicates in the bam, and i have read from a few issues here and here that a deduplicated (not just marked duplicate) bam is best for msisensor msi. therefore, we have to run an extra step and use almost twice as much storage to run msisensor from a deduplicated bam. ignoring dup reads from marked bam would avoid the trouble while hopefully not adding to the run time of msisensor

anoronh4 avatar Nov 10 '20 18:11 anoronh4

Sure. We will provide this option soon.

Beifang avatar Nov 11 '20 05:11 Beifang