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TCGA sample mapping?

Open sigven opened this issue 6 years ago • 7 comments

Hi, Thanks for a very comprehensive resource! I have compiled a list of unique diagnoses assigned to TCGA patients/samples. I was wondering whether there exist a mapping somewhere between OncoTree codes and the diagnoses/primary_tissues assigned to TCGA samples? Since OncoTree is used in cBioPortal, I reckoned that this may exist somewhere, but I may be wrong.

regards, Sigve

sigven avatar Aug 16 '19 09:08 sigven

@sigven Here is the mapping: TCGA_ONCOTREE_MAPPINGS.xlsx Let us know if you have any questions.

ritikakundra avatar Aug 27 '19 22:08 ritikakundra

Hi @ritikakundra, Thanks for the response. Considering the > 100 different tumor subtypes/diagnoses within TCGA samples which I pointed to, this mapping was not exactly what I was looking for. The mapping you point to refers to the main tumor types only. Considering the depth and detailed subtypes within OncoTree, I was looking for a more fine-grained mapping. I guess then that this mapping is not something you or others have at hand?

best, Sigve

sigven avatar Aug 29 '19 09:08 sigven

All TCGA samples in the portal do have an oncotree assigned to them. I think I can get you that too based on your list.


From: Sigve Nakken [email protected] Sent: Thursday, August 29, 2019 5:11:03 AM To: cBioPortal/oncotree Cc: Kundra, Ritika/Sloan Kettering Institute; Mention Subject: [EXTERNAL] Re: [cBioPortal/oncotree] TCGA sample mapping? (#200)

Hi @ritikakundrahttps://github.com/ritikakundra, Thanks for the response. Considering the > 100 different tumor subtypes/diagnoses within TCGA samples which I pointed to, this mapping was not exactly what I was looking for. The mapping you point to refers to the main tumor types only. Considering the depth and detailed subtypes within OncoTree, I was looking for a more fine-grained mapping. I guess then that this mapping is not something you or others have at hand?

best, Sigve

— You are receiving this because you were mentioned. Reply to this email directly, view it on GitHubhttps://github.com/cBioPortal/oncotree/issues/200?email_source=notifications&email_token=AC3TTNVCSQRNEFJ4WZFGVFDQG6HCPA5CNFSM4IMF2FH2YY3PNVWWK3TUL52HS4DFVREXG43VMVBW63LNMVXHJKTDN5WW2ZLOORPWSZGOD5N2BPI#issuecomment-526098621, or mute the threadhttps://github.com/notifications/unsubscribe-auth/AC3TTNUP54PYVTHMSJ7ATGTQG6HCPANCNFSM4IMF2FHQ.

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ritikakundra avatar Aug 29 '19 15:08 ritikakundra

Hi @ritikakundra, Thanks for the response. Considering the > 100 different tumor subtypes/diagnoses within TCGA samples which I pointed to, this mapping was not exactly what I was looking for. The mapping you point to refers to the main tumor types only. Considering the depth and detailed subtypes within OncoTree, I was looking for a more fine-grained mapping. I guess then that this mapping is not something you or others have at hand?

best, Sigve

I'm looking for this mapping file too, was there any solution to this issue in the end?

yesitsjess avatar Dec 17 '20 10:12 yesitsjess

Hello Looking for that mapping as well.

Best,

jkobject avatar Jun 02 '22 18:06 jkobject

It wasn't quite what I was looking for, but this might be useful: https://bioconductor.org/packages/devel/bioc/vignettes/BiocOncoTK/inst/doc/maptcga.html

yesitsjess avatar Jun 06 '22 13:06 yesitsjess

Yes so I guess TCGA does just have 35 tumor types? (compared to the >800 that oncotree lists).

jkobject avatar Jun 06 '22 14:06 jkobject