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Minimum Required Columns for `topSNPs` File?

Open laleoarrow opened this issue 1 year ago • 0 comments

Hello! Thank you for your fantastic work and contributions. I encountered a bit of confusion regarding the column requirements for the topSNPs file.

Problem Description

In the topSNPs example file, I noticed there are many columns, which makes it unclear which columns are strictly necessary. Could you clarify the minimum required columns for the topSNPs file? For example, would a file containing only significant lead SNPs or significant independent lead SNPs from FUMA be sufficient?

Desired Assistance

If possible, could you provide:

  • A clear list of required vs. optional columns for the topSNPs file?
  • Confirmation of whether files containing only significant lead SNPs or significant independent lead SNPs from FUMA would meet the requirements?

A simplified example of the topSNPs file format or a list of necessary columns with optional indicators would be incredibly helpful for setting up the data correctly.

Thank you very much for your time and assistance!


laleoarrow avatar Nov 13 '24 16:11 laleoarrow