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Package unusable in a workflow with other spatial tools due to python dependency pinning. Please update

Open rushin682 opened this issue 8 months ago • 0 comments

Dear authors,

This is a really amazing project and tool for registration in spatial-omics. Thank you very much.

However, it's nearly impossible to use the tool in a workflow with other tools for various downstream tasks, mainly due to the pinning of every python dependency package. Because of these explicit pins, we need to have 2 different virtual environments, one exclusively for STalign and other for everything else, which is less than ideal.

I kindly request you to update the dependency list (possibly also update the repository with updated python packaging tools (i.e with pyproject.toml configurations) instead of setup.py.

To get started, I have created a loosened dependency list (Attached): requirements.txt. This works for aligning ST and histology (i.e Tutorial 3) but I haven't tested it with other functionalities. I kindly request you to do so as well.

I am happy to answer any questions and also help in updating the repository if required.

Thank you for your time and effort on this project.

best, Rushin

rushin682 avatar Aug 12 '25 13:08 rushin682