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Implement the free-rate model of rates across sites

Open alexeid opened this issue 7 years ago • 3 comments

The developers may consider incorporating the free-rate model, which relaxes the assumption of Gamma rate heterogeneity without many more parameters (https://doi.org/10.1038/nmeth.4285). One can for example use Dirichlet prior for rate proportions.

alexeid avatar Jan 14 '19 21:01 alexeid

There is already an implementation in the RBS package: FreeRateModel with example XML. Operators/priors may slightly differ in the implementation from the citation though.

rbouckaert avatar Jan 15 '19 22:01 rbouckaert

Validated and tested?

On 16/01/2019, at 11:58 AM, Remco Bouckaert [email protected] wrote:

There is already an implementation in the RBS package: FreeRateModel https://github.com/BEAST2-Dev/rb-beast/blob/master/src/beast/evolution/sitemodel/FreeRateModel.java with example XML https://github.com/BEAST2-Dev/rb-beast/blob/master/examples/testFreeRateModel.xml. Operators/priors may slightly differ in the implementation from the citation though.

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alexeid avatar Jan 15 '19 23:01 alexeid

Tested, not validated.

rbouckaert avatar Jan 16 '19 22:01 rbouckaert