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Incorporate RNAplex model with seed heuristic

Open martin-raden opened this issue 9 years ago • 2 comments

  • include RNAplex model
  • enable seed heuristic
  • enable nested + pseudoknot accessibilities

martin-raden avatar Nov 25 '16 12:11 martin-raden

accessibility computation models to be tested

  • RNAplex
  • Accessfold
  • NUPACK-based

martin-raden avatar Sep 19 '19 11:09 martin-raden

concerning NUPACK

NUPACK enables the computation of (position-wise) unpaired probabilities. These could be incorporated in a AccessFold-like approach to incorporate pseudoknotted intramolecular structure into the interaction prediction.

Two options:

  • read Pu values from NUPACK ppairs output file
  • use NUPACK library for direct computation (check if possible)

martin-raden avatar Sep 19 '19 11:09 martin-raden