Extension icons don't support alternate Libre Calc UI Styles
When using any user interface style other than the "Standard Toolbar" in LibreCalc(View > User Interface > select UI variant), the Libre Pythonista icons are not available. It should be placed into the "Extensions" tab, and not as a toolbar. There is a member in the LibreOffice Telegram group who is familiar with this issue and has implemented a solution in another extension.
Any extension that does not support this will not work with the other UIs. You can find more information at the following link: Zotero LibreOffice Integration.
Additionally, you can check the lines there, as they are also included in the wiki: NotebookBar Extensions. This wiki page describes how to add support for Glade UIs, including the Tabbed UI.